VECTOR-HOST INTERACTIONS AND TRANSMISSION OF ARBOVIRUSES IN THE U.S.

 

Goudarz Molaei

 

Center for Vector Biology & Zoonotic Diseases

The Connecticut Agricultural Experiment Station

123 Huntington Street, P.O. Box 1106

New Haven, CT 06504

Goudarz.Molaei@po.state.ct.us

 

 

ABSTRACT

Knowledge of the vector-host interactions is essential for evaluating the role of mosquitoes in transmission of vector-borne zoonotic pathogens and for assessing the contribution of various vertebrates as reservoir and amplifying hosts. Our studies on the bloodmeal host utilization by potential mosquito vectors of arboviruses in the U.S. indicate that while some mosquito species predominantly feed on avian hosts, and focus feeding activity on several key birds, other species indiscriminately feed on both birds and mammals. The importance of heterogeneity in vector-host interactions and implication for transmission of arboviruses will be discussed. Studies on the genetic structure and potential influence of introgressions on the bloodmeal host utilization by mosquitoes will also be reviewed. 

Key words. Mosquito, host-feeding pattern, mitochondrial cytochrome b gene, West Nile virus, Northeastern USA